Max Verstappen remporte le Grand Prix du Mexique devant Lewis Hamilton et Sergio Perez. Pierre Gasly finit 4e devant les Ferrari. Sebastian Vettel termine 7e et Kimi Räikkönen est 8e. Fernando Alonso et Lando Norris sont les derniers du top 10.
| Pos | No | Pilote | Équipe | Tours | Temps | PTS |
|---|---|---|---|---|---|---|
| 1 | 33 | Max Verstappen | Red Bull Racing Honda | 71 | 1:38:39.086 | 25 |
| 2 | 44 | Lewis Hamilton | Mercedes | 71 | +16.555s | 18 |
| 3 | 11 | Sergio Perez | Red Bull Racing Honda | 71 | +17.752s | 15 |
| 4 | 10 | Pierre Gasly | AlphaTauri Honda | 71 | +63.845s | 12 |
| 5 | 16 | Charles Leclerc | Ferrari | 71 | +81.037s | 10 |
| 6 | 55 | Carlos Sainz | Ferrari | 70 | +1 lap | 8 |
| 7 | 5 | Sebastian Vettel | Aston Martin Mercedes | 70 | +1 lap | 6 |
| 8 | 7 | Kimi Räikkönen | Alfa Romeo Racing Ferrari | 70 | +1 lap | 4 |
| 9 | 14 | Fernando Alonso | Alpine Renault | 70 | +1 lap | 2 |
| 10 | 4 | Lando Norris | McLaren Mercedes | 70 | +1 lap | 1 |
| 11 | 99 | Antonio Giovinazzi | Alfa Romeo Racing Ferrari | 70 | +1 lap | 0 |
| 12 | 3 | Daniel Ricciardo | McLaren Mercedes | 70 | +1 lap | 0 |
| 13 | 31 | Esteban Ocon | Alpine Renault | 70 | +1 lap | 0 |
| 14 | 18 | Lance Stroll | Aston Martin Mercedes | 69 | +2 laps | 0 |
| 15 | 77 | Valtteri Bottas | Mercedes | 69 | +2 laps | 0 |
| 16 | 63 | George Russell | Williams Mercedes | 69 | +2 laps | 0 |
| 17 | 6 | Nicholas Latifi | Williams Mercedes | 69 | +2 laps | 0 |
| 18 | 9 | Nikita Mazepin | Haas Ferrari | 68 | +3 laps | 0 |
| NC | 47 | Mick Schumacher | Haas Ferrari | 0 | DNF | 0 |
| NC | 22 | Yuki Tsunoda | AlphaTauri Honda | 0 | DNF |
Meilleur tour: Valtteri Bottas en 1:17.774 au 69e tour