Jenson Button (McLaren) a remporté le Grand Prix du Japon. Sebastian Vettel (Red Bull) en terminant 3e est devenu le plus jeune double champion du monde à 24 ans. Fernando Alonso (Ferrari) a terminé 2e. Mark Webber (Red Bull) termine 4e, devant Lewis Hamilton (McLaren). Michael Schumacher (Mercedes) fini 6e. Nico Rosberg (Mercedes) termine 10e, lui qui partait avant dernier.
| 1 | 4 | Jenson Button | McLaren-Mercedes | 53 | 1:30:53.427 | 2 | 25 |
| 2 | 5 | Fernando Alonso | Ferrari | 53 | +1.1 secs | 5 | 18 |
| 3 | 1 | Sebastian Vettel | RBR-Renault | 53 | +2.0 secs | 1 | 15 |
| 4 | 2 | Mark Webber | RBR-Renault | 53 | +8.0 secs | 6 | 12 |
| 5 | 3 | Lewis Hamilton | McLaren-Mercedes | 53 | +24.2 secs | 3 | 10 |
| 6 | 7 | Michael Schumacher | Mercedes | 53 | +27.1 secs | 8 | 8 |
| 7 | 6 | Felipe Massa | Ferrari | 53 | +28.2 secs | 4 | 6 |
| 8 | 17 | Sergio Perez | Sauber-Ferrari | 53 | +39.3 secs | 17 | 4 |
| 9 | 10 | Vitaly Petrov | Renault | 53 | +42.6 secs | 10 | 2 |
| 10 | 8 | Nico Rosberg | Mercedes | 53 | +44.3 secs | 23 | 1 |
| 11 | 14 | Adrian Sutil | Force India-Mercedes | 53 | +54.4 secs | 11 | |
| 12 | 15 | Paul di Resta | Force India-Mercedes | 53 | +62.3 secs | 12 | |
| 13 | 16 | Kamui Kobayashi | Sauber-Ferrari | 53 | +63.7 secs | 7 | |
| 14 | 12 | Pastor Maldonado | Williams-Cosworth | 53 | +64.1 secs | 14 | |
| 15 | 19 | Jaime Alguersuari | STR-Ferrari | 53 | +66.6 secs | 16 | |
| 16 | 9 | Bruno Senna | Renault | 53 | +72.6 secs | 9 | |
| 17 | 11 | Rubens Barrichello | Williams-Cosworth | 53 | +74.1 secs | 13 | |
| 18 | 20 | Heikki Kovalainen | Lotus-Renault | 53 | +87.8 secs | 18 | |
| 19 | 21 | Jarno Trulli | Lotus-Renault | 53 | +96.1 secs | 19 | |
| 20 | 24 | Timo Glock | Virgin-Cosworth | 51 | +2 Laps | 21 | |
| 21 | 25 | Jerome d’Ambrosio | Virgin-Cosworth | 51 | +2 Laps | 20 | |
| 22 | 22 | Daniel Ricciardo | HRT-Cosworth | 51 | +2 Laps | 22 | |
| 23 | 23 | Vitantonio Liuzzi | HRT-Cosworth | 50 | +3 Laps | 24 | |
| Ret | 18 | Sebastien Buemi | STR-Ferrari | 11 | Wheel | 15 |
Meilleur tour: Jenson Button en 1:36.568 au 52e tour