Sébastian Vettel remporte le Grand Prix du Brésil devant Valtteri Bottas et Kimi Räikkönen. Lewis Hamilton parti des puits, a terminé 4e. On retrouve ensuite les 2 pilotes Red Bull. Felipe Massa termine 7e a son dernier Grand Prix à domicile.
| Pos | No | Pilote | Équipe | Tours | Temps | Pts |
|---|
| 1 | 5 | Sebastian Vettel | Ferrari | 71 | 1:31:26.262 | 25 |
| 2 | 77 | Valtteri Bottas | Mercedes | 71 | +2.762s | 18 |
| 3 | 7 | Kimi Räikkönen | Ferrari | 71 | +4.600s | 15 |
| 4 | 44 | Lewis Hamilton | Mercedes | 71 | +5.468s | 12 |
| 5 | 33 | Max Verstappen | Red Bull Racing TAG Heuer | 71 | +32.940s | 10 |
| 6 | 3 | Daniel Ricciardo | Red Bull Racing TAG Heuer | 71 | +48.691s | 8 |
| 7 | 19 | Felipe Massa | Williams Mercedes | 71 | +68.882s | 6 |
| 8 | 14 | Fernando Alonso | McLaren Honda | 71 | +69.363s | 4 |
| 9 | 11 | Sergio Perez | Force India Mercedes | 71 | +69.500s | 2 |
| 10 | 27 | Nico Hulkenberg | Renault | 70 | +1 lap | 1 |
| 11 | 55 | Carlos Sainz | Renault | 70 | +1 lap | 0 |
| 12 | 10 | Pierre Gasly | Toro Rosso | 70 | +1 lap | 0 |
| 13 | 9 | Marcus Ericsson | Sauber Ferrari | 70 | +1 lap | 0 |
| 14 | 94 | Pascal Wehrlein | Sauber Ferrari | 70 | +1 lap | 0 |
| 15 | 8 | Romain Grosjean | Haas Ferrari | 69 | +2 laps | 0 |
| 16 | 18 | Lance Stroll | Williams Mercedes | 69 | +2 laps | 0 |
| NC | 28 | Brendon Hartley | Toro Rosso | 40 | DNF | 0 |
| NC | 31 | Esteban Ocon | Force India Mercedes | 0 | DNF | 0 |
| NC | 2 | Stoffel Vandoorne | McLaren Honda | 0 | DNF | 0 |
| NC | 20 | Kevin Magnussen | Haas Ferrari | 0 | DNF | 0 |
Meilleur tour: Max Verstappen en 1:11.044 au 64e tour
