Max Verstappen et Daniel Ricciardo ont de nouveau été les plus rapide au Mexique. Carlos Sainz a fait le 3e temps et Sebastian Vettel est 4e. On retrouve ensuite Nico Hulkenberg, Brendon Hartley et Lewis Hamilton.
| Pos | No | Pilote | Équipe | Temps | Écart | Tours |
|---|---|---|---|---|---|---|
| 1 | 33 | Max Verstappen | Red Bull Racing TAG Heuer | 1:16.720 | 21 | |
| 2 | 3 | Daniel Ricciardo | Red Bull Racing TAG Heuer | 1:16.873 | +0.153s | 32 |
| 3 | 55 | Carlos Sainz | Renault | 1:17.953 | +1.233s | 35 |
| 4 | 5 | Sebastian Vettel | Ferrari | 1:17.954 | +1.234s | 42 |
| 5 | 27 | Nico Hulkenberg | Renault | 1:18.046 | +1.326s | 36 |
| 6 | 28 | Brendon Hartley | Scuderia Toro Rosso Honda | 1:18.061 | +1.341s | 35 |
| 7 | 44 | Lewis Hamilton | Mercedes | 1:18.100 | +1.380s | 40 |
| 8 | 7 | Kimi Räikkönen | Ferrari | 1:18.133 | +1.413s | 42 |
| 9 | 77 | Valtteri Bottas | Mercedes | 1:18.140 | +1.420s | 40 |
| 10 | 11 | Sergio Perez | Force India Mercedes | 1:18.167 | +1.447s | 24 |
| 11 | 31 | Esteban Ocon | Force India Mercedes | 1:18.485 | +1.765s | 24 |
| 12 | 8 | Romain Grosjean | Haas Ferrari | 1:18.733 | +2.013s | 39 |
| 13 | 16 | Charles Leclerc | Sauber Ferrari | 1:19.024 | +2.304s | 39 |
| 14 | 10 | Pierre Gasly | Scuderia Toro Rosso Honda | 1:19.047 | +2.327s | 36 |
| 15 | 2 | Stoffel Vandoorne | McLaren Renault | 1:19.096 | +2.376s | 30 |
| 16 | 18 | Lance Stroll | Williams Mercedes | 1:19.219 | +2.499s | 25 |
| 17 | 9 | Marcus Ericsson | Sauber Ferrari | 1:19.322 | +2.602s | 41 |
| 18 | 35 | Sergey Sirotkin | Williams Mercedes | 1:19.335 | +2.615s | 37 |
| 19 | 14 | Fernando Alonso | McLaren Renault | 1:19.543 | +2.823s | 31 |
| 20 | 20 | Kevin Magnussen | Haas Ferrari | 1:19.670 | +2.950s | 35 |