Max Verstappen remporte le Grand Prix des États-Unis devant Lewis Hamilton et Sergio Perez. Charles Leclerc est 4e. Daniel Ricciardo finit 5e. Valtteri Bottas est 6e et Carlos Sainz est 7e. Lando Norris, Yuki Tsunoda et Sebastian Vettel récoltent les derniers points disponible.
| Pos | No | Pilote | Équipe | Tours | Temps | PTS |
|---|---|---|---|---|---|---|
| 1 | 33 | Max Verstappen | Red Bull Racing Honda | 56 | 1:34:36.552 | 25 |
| 2 | 44 | Lewis Hamilton | Mercedes | 56 | +1.333s | 19 |
| 3 | 11 | Sergio Perez | Red Bull Racing Honda | 56 | +42.223s | 15 |
| 4 | 16 | Charles Leclerc | Ferrari | 56 | +52.246s | 12 |
| 5 | 3 | Daniel Ricciardo | McLaren Mercedes | 56 | +76.854s | 10 |
| 6 | 77 | Valtteri Bottas | Mercedes | 56 | +80.128s | 8 |
| 7 | 55 | Carlos Sainz | Ferrari | 56 | +83.545s | 6 |
| 8 | 4 | Lando Norris | McLaren Mercedes | 56 | +84.395s | 4 |
| 9 | 22 | Yuki Tsunoda | AlphaTauri Honda | 55 | +1 lap | 2 |
| 10 | 5 | Sebastian Vettel | Aston Martin Mercedes | 55 | +1 lap | 1 |
| 11 | 99 | Antonio Giovinazzi | Alfa Romeo Racing Ferrari | 55 | +1 lap | 0 |
| 12 | 18 | Lance Stroll | Aston Martin Mercedes | 55 | +1 lap | 0 |
| 13 | 7 | Kimi Räikkönen | Alfa Romeo Racing Ferrari | 55 | +1 lap | 0 |
| 14 | 63 | George Russell | Williams Mercedes | 55 | +1 lap | 0 |
| 15 | 6 | Nicholas Latifi | Williams Mercedes | 55 | +1 lap | 0 |
| 16 | 47 | Mick Schumacher | Haas Ferrari | 54 | +2 laps | 0 |
| 17 | 9 | Nikita Mazepin | Haas Ferrari | 54 | +2 laps | 0 |
| NC | 14 | Fernando Alonso | Alpine Renault | 49 | DNF | 0 |
| NC | 31 | Esteban Ocon | Alpine Renault | 40 | DNF | 0 |
| NC | 10 | Pierre Gasly | AlphaTauri Honda | 14 | DNF | 0 |
Meilleur tour: Lewis Hamilton en 1:38.485 au 41e tour