Max Verstappen a finit premier de la 2e séance d’essais libres du Grand Prix du Mexique. Les Mercedes suivent, ainsi que Sergio Perez. Carlos Sainz est 5e devant Pierre Gasly. Charles Leclerc a fait le 7e temps. Yuki Tsunoda , Sebastian Vettel et Fernando Alonso sont du top 10.
| Pos | No | Pilote | Équipe | Temps | Écart | Tours |
|---|---|---|---|---|---|---|
| 1 | 33 | Max Verstappen | Red Bull Racing Honda | 1:17.301 | 28 | |
| 2 | 77 | Valtteri Bottas | Mercedes | 1:17.725 | +0.424s | 31 |
| 3 | 44 | Lewis Hamilton | Mercedes | 1:17.810 | +0.509s | 26 |
| 4 | 11 | Sergio Perez | Red Bull Racing Honda | 1:17.871 | +0.570s | 26 |
| 5 | 55 | Carlos Sainz | Ferrari | 1:18.318 | +1.017s | 29 |
| 6 | 10 | Pierre Gasly | AlphaTauri Honda | 1:18.429 | +1.128s | 29 |
| 7 | 16 | Charles Leclerc | Ferrari | 1:18.605 | +1.304s | 28 |
| 8 | 22 | Yuki Tsunoda | AlphaTauri Honda | 1:18.644 | +1.343s | 31 |
| 9 | 5 | Sebastian Vettel | Aston Martin Mercedes | 1:18.681 | +1.380s | 32 |
| 10 | 14 | Fernando Alonso | Alpine Renault | 1:18.732 | +1.431s | 27 |
| 11 | 7 | Kimi Räikkönen | Alfa Romeo Racing Ferrari | 1:18.841 | +1.540s | 25 |
| 12 | 4 | Lando Norris | McLaren Mercedes | 1:18.979 | +1.678s | 27 |
| 13 | 99 | Antonio Giovinazzi | Alfa Romeo Racing Ferrari | 1:19.227 | +1.926s | 31 |
| 14 | 31 | Esteban Ocon | Alpine Renault | 1:19.431 | +2.130s | 37 |
| 15 | 3 | Daniel Ricciardo | McLaren Mercedes | 1:19.521 | +2.220s | 7 |
| 16 | 47 | Mick Schumacher | Haas Ferrari | 1:19.620 | +2.319s | 30 |
| 17 | 18 | Lance Stroll | Aston Martin Mercedes | 1:19.730 | +2.429s | 36 |
| 18 | 6 | Nicholas Latifi | Williams Mercedes | 1:20.820 | +3.519s | 17 |
| 19 | 9 | Nikita Mazepin | Haas Ferrari | 1:21.581 | +4.280s | 28 |
| 20 | 63 | George Russell | Williams Mercedes | 2 |