Sebastian Vettel a finit en tête des essais libres du vendredi au Mexique. Max Verstappen a devancé Charles Leclerc et les Mercedes. On retrouve ensuite les Toro Rosso. En plus des McLaren, il a aussi Nico Hulkenberg dans le top 10.
| Pos | No | Pilote | Équipe | Temps | Écart | Tours |
|---|---|---|---|---|---|---|
| 1 | 5 | Sebastian Vettel | Ferrari | 1:16.607 | 35 | |
| 2 | 33 | Max Verstappen | Red Bull Racing Honda | 1:16.722 | +0.115s | 37 |
| 3 | 16 | Charles Leclerc | Ferrari | 1:17.072 | +0.465s | 34 |
| 4 | 77 | Valtteri Bottas | Mercedes | 1:17.221 | +0.614s | 39 |
| 5 | 44 | Lewis Hamilton | Mercedes | 1:17.570 | +0.963s | 35 |
| 6 | 26 | Daniil Kvyat | Scuderia Toro Rosso Honda | 1:17.747 | +1.140s | 40 |
| 7 | 10 | Pierre Gasly | Scuderia Toro Rosso Honda | 1:18.003 | +1.396s | 39 |
| 8 | 55 | Carlos Sainz | McLaren Renault | 1:18.079 | +1.472s | 38 |
| 9 | 27 | Nico Hulkenberg | Renault | 1:18.261 | +1.654s | 23 |
| 10 | 4 | Lando Norris | McLaren Renault | 1:18.349 | +1.742s | 36 |
| 11 | 18 | Lance Stroll | Racing Point BWT Mercedes | 1:18.362 | +1.755s | 38 |
| 12 | 11 | Sergio Perez | Racing Point BWT Mercedes | 1:18.366 | +1.759s | 34 |
| 13 | 3 | Daniel Ricciardo | Renault | 1:18.380 | +1.773s | 34 |
| 14 | 7 | Kimi Räikkönen | Alfa Romeo Racing Ferrari | 1:18.681 | +2.074s | 37 |
| 15 | 8 | Romain Grosjean | Haas Ferrari | 1:18.766 | +2.159s | 37 |
| 16 | 99 | Antonio Giovinazzi | Alfa Romeo Racing Ferrari | 1:18.889 | +2.282s | 46 |
| 17 | 20 | Kevin Magnussen | Haas Ferrari | 1:19.306 | +2.699s | 37 |
| 18 | 63 | George Russell | Williams Mercedes | 1:19.968 | +3.361s | 36 |
| 19 | 88 | Robert Kubica | Williams Mercedes | 1:20.180 | +3.573s | 37 |
| 20 | 23 | Alexander Albon | Red Bull Racing Honda | 1:21.665 | +5.058s | 5 |